Книги автора Hugo Kubinyi

With its particular emphasis on the constitutive activity of G-protein-coupled receptors (GPCRs)s, this book comprehensively discusses an im…

Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug deve…

This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information that…

This first overview of mass spectrometry-based pharmaceutical analysis is the key to improved high-throughput drug screening, rational drug …

This handbook provides the first-ever inside view of today's integrated approach to rational drug design. Chemoinformatics experts from larg…

Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development pr…

This handbook is the first to address the practical aspects of this novel method. It provides a complete overview of the field and progresse…

Most drugs bind to a clearly defined macromolecular target that is complementary in terms of structure and chemistry. This observation is th…

Quantitative studies on structure-activity and structure-property relationships are powerful tools in directed drug research. In recent year…

This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in d…

Computational methods are transforming the work of chemical and pharmaceutical laboratories. Increasingly faster and more exact simulation a…

The lock-and-key principle formulated by Emil Fischer as early as the end of the 19th century has still not lost any of its significance for…

Written by experienced experts in molecular modeling, this books describes the basics to the extent that is necessary if one wants to be abl…

This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applic…

Barrier, reservoir, target site – those are but some of the possible functions of biological lipid membranes in the complex interplay of dru…

Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosteris…

Tailored to the needs of scientists developing drugs, chemicals, cosmetics and other products this one-stop reference for medicinal chemists…

Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential f…

This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring…

In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The fir…