Книги автора Hugo Kubinyi

This first overview of mass spectrometry-based pharmaceutical analysis is the key to improved high-throughput drug screening, rational drug …

In this new edition of a bestseller, all the contents have been updated and new material has been added, especially in the areas of toxicity…

Edited by two experts working at the pioneering pharmaceutical company and major global player in hormone-derived drugs, this handbook and r…

Recent progress in high-throughput screening, combinatorial chemistry and molecular biology has radically changed the approach to drug disco…

The authors of this guide are experts on the use of microwaves for drug synthesis as well as having much experience in teaching courses held…

The new edition of this practice-oriented handbook features thoroughly updated contents, including recent developments in parallel synthesis…

With its particular emphasis on the constitutive activity of G-protein-coupled receptors (GPCRs)s, this book comprehensively discusses an im…

Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug deve…

This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information that…

In keeping with the outstanding importance of lipophilicity in biosciences, this volume examines all its facets in more than twenty contribu…

Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development pr…

This handbook is the first to address the practical aspects of this novel method. It provides a complete overview of the field and progresse…

Most drugs bind to a clearly defined macromolecular target that is complementary in terms of structure and chemistry. This observation is th…

Computational methods are transforming the work of chemical and pharmaceutical laboratories. Increasingly faster and more exact simulation a…

The lock-and-key principle formulated by Emil Fischer as early as the end of the 19th century has still not lost any of its significance for…

The peroral application (swallowing) of a medicine means that the body must first resorb the active substance before it can begin to take ef…

This practice-oriented handbook surveys current knowledge on the prediction and prevention of adverse drug reactions related to off-target a…

The vast progress made in the investigation of biomolecules using NMR has only recently been rewarded with the Nobel Prize for Kurt Wuthrich…

Barrier, reservoir, target site – those are but some of the possible functions of biological lipid membranes in the complex interplay of dru…

Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosteris…