Catholic Churchmen in Science. First Series

Unfortunately for most of the good stories of history, modern criticism has nearly always failed to find any authentic basis for them, and they have had to go the way of the legends of Washington's hatchet and Tell's apple. We are sorry to say that that seems to be true also of this particular story. Antimony, the word, is very probably derived from certain dialectic forms of the Greek word for the metal, and the name is no more derived from anti and monachus than it is from anti and monos (opposed to single existence), another fictitious derivation that has been suggested, and one whose etymological value is supposed to consist in the fact that antimony is practically never found alone in nature.

Notwithstanding the apparent cloud of unfounded traditions that are associated with his name, there can be no doubt at all of the fact that Valentinus–to give him the Latin name by which he is commonly designated in foreign literatures–was one of the great geniuses who, working in obscurity, make precious steps into the unknown that enable humanity after them to see things more clearly than ever before. There are definite historical grounds for placing Basil Valentine as the first of the series of careful observers who differentiated chemistry from the old alchemy and applied its precious treasures of information to the uses of medicine. It was because of the study of Basil Valentine's work that Paracelsus broke away from the Galenic traditions, so supreme in medicine up to his time, and began our modern pharmaceutics. Following on the heels of Paracelsus came Van Helmont, the father of modern medical chemistry, and these three did more than any others to enlarge the scope of medication and to make observation rather than authority the most important criterion of truth in medicine. Indeed, the work of these three men dominated medicine, or at least the department of pharmaceutics, down almost to our own day, and their influence is still felt in drug-giving.

While we do not know the absolute date of either the birth or the death of Basil Valentine and are not sure even of the exact period in which he lived and did his work, we are sure that a great original observer about the time of the invention of printing studied mercury and sulphur and various salts, and above all, introduced antimony to the notice of the scientific world, and especially to the favor of practitioners of medicine. His book, "The Triumphal Chariot of Antimony," is full of conclusions not quite justified by his premises nor by his observations. There is no doubt, however, that the observational methods which he employed did give an immense amount of knowledge and formed the basis of the method of investigation by which the chemical side of medicine was to develop during the next two or three centuries. Great harm was done by the abuse of antimony, but then great harm is done by the abuse of anything, no matter how good it may be. For a time it came to be the most important drug in medicine and was only replaced by venesection.

The fact of the matter is that doctors were looking for effects from their drugs, and antimony is, above all things, effective. Patients, too, wished to see the effect of the medicines they took. They do so even yet, and when antimony was administered there was no doubt about its working.

Some five years ago, when Sir Michael Foster, M.D., professor of physiology in the University of Cambridge, England, was invited to deliver the Lane lectures at the Cooper Medical College, in San Francisco, he took for his subject "The History of Physiology." In the course of his lecture on "The Rise of Chemical Physiology" he began with the name of Basil Valentine, who first attracted men's attention to the many chemical substances around them that might be used in the treatment of disease, and said of him:–

He was one of the alchemists, but in addition to his inquiries into the properties of metals and his search for the philosopher's stone, he busied himself with the nature of drugs, vegetable and mineral, and with their action as remedies for disease. He was no anatomist, no physiologist, but rather what nowadays we should call a pharmacologist. He did not care for the problem of the body, all he sought to understand was how the constituents of the soil and of plants might be treated so as to be available for healing the sick and how they produced their effects. We apparently owe to him the introduction of many chemical substances, for instance, of hydrochloric acid, which he prepared from oil of vitriol and salt, and of many vegetable drugs. And he was apparently the author of certain conceptions which, as we shall see, played an important part in the development of chemistry and of physiology. To him, it seems, we owe the idea of the three "elements," as they were and have been called, replacing the old idea of the ancients of the four elements–earth, air, fire, and water. It must be remembered, however, that both in the ancient and in the new idea the word "element" was not intended to mean that which it means to us now, a fundamental unit of matter, but a general quality or property of matter. The three elements of Valentine were (1) sulphur, or that which is combustible, which is changed or destroyed, or which at all events disappears during burning or combustion; (2) mercury, that which temporarily disappears during burning or combustion, which is dissociated in the burning from the body burnt, but which may be recovered, that is to say, that which is volatile, and (3) salt, that which is fixed, the residue or ash which remains after burning.

The most interesting of Basil Valentine's books, and the one which has had the most enduring influence, is undoubtedly "The Triumphal Chariot of Antimony." It has been translated and has had a wide vogue in every language of modern Europe. Its recommendation of antimony had such an effect upon medical practice that it continued to be the most important drug in the pharmacopoeia down almost to the middle of the nineteenth century. If any proof were needed that Basil Valentine or that the author of the books that go under that name was a monk, it would be found in the introduction to this volume, which not only states that fact very clearly, but also in doing so makes use of language that shows the writer to have been deeply imbued with the old monastic spirit. I quote the first paragraph of this introduction in order to make clear what I mean. The quotation is taken from the English translation of the work as published in London in 1678. Curiously enough, seeing the obscurity surrounding Valentine himself, we do not know for sure who made the translation. The translator apologizes somewhat for the deeply religious spirit of the book, but considers that he was not justified in eliminating any of this. Of course, the translation is left in the quaint old-fashioned form so eminently suited to the thoughts of the old master, and the spelling and use of capitals is not changed:

Basil Valentine–His Triumphant Chariot of Antimony Since I, Basil Valentine, by Religious Vows am bound to live according to the Order of St. Benedict, and that requires another manner of spirit of Holiness than the common state of Mortals exercised in the profane business of this World; I thought it my duty before all things, in the beginning of this little book, to declare what is necessary to be known by the pious Spagyrist [old-time name for medical chemist], inflamed with an ardent desire of this Art, as what he ought to do, and whereunto to direct his aim, that he may lay such foundations of the whole matter as may be stable; lest his Building, shaken with the Winds, happen to fall, and the whole Edifice to be involved in shameful Ruine, which otherwise, being founded on more firm and solid principles, might have continued for a long series of time Which Admonition I judged was, is and always will be a necessary part of my Religious Office; especially since we must all die, and no one of us which are now, whether high or low, shall long be seen among the number of men For it concerns me to recommend these Meditations of Mortality to Posterity, leaving them behind me, not only that honor may be given to the Divine Majesty, but also that Men may obey him sincerely in all things.

In this my Meditation I found that there were five principal heads, chiefly to be considered by the wise and prudent spectators of our Wisdom and Art. The first of which is, Invocation of God. The second, Contemplation of Nature The third, True Preparation. The fourth, the Way of Using. The fifth, Utility and Fruit. For he who regards not these, shall never obtain place among true Chymists, or fill up the number of perfect Spagyrists. Therefore, touching these five heads, we shall here following treat and so far declare them, as that the general Work may be brought to light and perfected by an intent and studious Operator.

This book, though the title might seem to indicate it, is not devoted entirely to the study of antimony, but contains many important additions to the chemistry of the time. For instance, Basil Valentine explains in this work how what he calls the spirit of salt might be obtained. He succeeded in manufacturing this material by treating common salt with oil of vitriol and heat. From the description of the uses to which he put the end product of his chemical manipulation, it is evident that under the name of spirit of salt he is describing what we now know as hydrochloric acid. This is the first definite mention of it in the history of science, and the method suggested for its preparation is not very different from that employed even at the present time. He also suggests in this volume how alcohol may be obtained in high strengths. He distilled the spirit obtained from wine over carbonate of potassium, and thus succeeded in depriving it of a great proportion of its water.

We have said that he was deeply interested in the philosopher's stone. Naturally this turned his attention to the study of metals, and so it is not surprising to find that he succeeded in formulating a method by which metallic copper could be obtained. The substance used for the purpose was copper pyrites, which was changed to an impure sulphate of copper by the action of oil of vitriol and moist air. The sulphate of copper occurred in solution, and the copper could be precipitated from it by plunging an iron bar into it. Basil Valentine recognized the presence of this peculiar yellow metal and studied some of its qualities. He does not seem to have been quite sure, however, whether the phenomenon that he witnessed was not really a transmutation of the iron into copper, as a consequence of the other chemicals present.

There are some observations on chemical physiology, and especially with regard to respiration, in the book on antimony which show their author to have anticipated the true explanation of the theory of respiration. He states that animals breathe, because the air is needed to support their life, and that all the animals exhibit the phenomenon of respiration. He even insists that the fishes, though living in water, breathe air, and he adduces in support of this idea the fact that whenever a river is entirely frozen the fishes die. The reason for this being, according to this old-time physiologist, not that the fishes are frozen to death, but that they are not able to obtain air in the ice as they did in the water, and consequently perish.

There are many testimonies to the practical character of all his knowledge and his desire to apply it for the benefit of humanity. The old monk could not repress the expression of his impatience with physicians who gave to patients for diseases of which they knew little, remedies of which they knew less. For him it was an unpardonable sin for a physician not to have faithfully studied the various mixtures that he prescribed for his patients, and not to know not only their appearance and taste and effect, but also the limits of their application. Considering that at the present time it is a frequent source of complaint that physicians often prescribe remedies with whose physical appearances they are not familiar, this complaint of the old-time chemist alchemist will be all the more interesting for the modern physician. It is evident that when Basil Valentine allows his ire to get the better of him it is because of his indignation over the quacks who were abusing medicine and patients in his time, as they have ever since. There is a curious bit of aspersion on mere book-learning in the passage that has a distinctly modern ring, and one feels the truth of Russell Lowell's expression that to read a great genius, no matter how antique, is like reading a commentary in the morning paper, so up-to-date does genius ever remain:–

And whensoever I shall have occasion to contend in the School with such a Doctor, who knows not how himself to prepare his own medicines, but commits that business to another, I am sure I shall obtain the Palm from him; for indeed that good man knows not what medicines he prescribes to the sick; whether the color of them be white, black, grey, or blew, he cannot tell; nor doth this wretched man know whether the medicine he gives be dry or hot, cold or humid; but he only knows that he found it so written in his Books, and thence pretends knowledge (or as it were, Possession) by Prescription of a very long time; yet he desires to further Information Here again let it be lawful to exclaim, Good God, to what a state is the matter brought! what goodness of minde is in these men! what care do they take of the sick! Wo, wo to them! in the day of Judgment they will find the fruit of their ignorance and rashness, then they will see Him whom they pierced, when they neglected their Neighbor, sought after money and nothing else; whereas were they cordial in their profession, they would spend Nights and Days in Labour that they might become more learned in their Art, whence more certain health would accrew to the sick with their Estimation and greater glory to themselves. But since Labour is tedious to them, they commit the matter to chance, and being secure of their Honour, and content with their Fame, they (like Brawlers) defend themselves with a certain garrulity, without any respect had to Confidence or Truth.

Perhaps one of the reasons why Valentine's book has been of such enduring interest is that it is written in an eminently human vein and out of a lively imagination. It is full of figures relating to many other things besides chemistry, which serve to show how deeply this investigating observer was attentive to all the problems of life around him. For instance, when he wants to describe the affinity that exists between many substances in chemistry, and which makes it impossible for them not to be attracted to one another, he takes a figure from the attractions that he sees exist among men and women. There are some paragraphs with regard to the influence of the passion of love that one might think rather a quotation from an old-time sermon than from a great ground-breaking book in the science of chemistry.

Love leaves nothing entire or sound in man; it impedes his sleep; he cannot rest either day or night; it takes off his appetite that he hath no disposition either to meat or drink by reason of the continual torments of his heart and mind. It deprives him of all Providence, hence he neglects his affairs, vocation and business. He minds neither study, labor nor prayer; casts away all thoughts of anything but the body beloved; this is his study, this his most vain occupation. If to lovers the success be not answerable to their wish, or so soon and prosperously as they desire, how many melancholies henceforth arise, with griefs and sadnesses, with which they pine away and wax so lean as they have scarcely any flesh cleaving to the bones Yea, at last they lose the life itself, as may be proved by many examples! for such men, (which is an horrible thing to think of) slight and neglect all perils and detriments, both of the body and life, and of the soul and eternal salvation

It is evident that human nature is not different in our sophisticated twentieth century from that which this observant old monk saw around him in the fifteenth. He continues:–

How many testimonies of this violence which is in love, are daily found? for it not only inflames the younger sort, but it so far exaggerates some persons far gone in years as through the burning heat thereof, they are almost mad Natural diseases are for the most part governed by the complexion of man and therefore invade some more fiercely, others more gently; but Love, without distinction of poor or rich, young or old, seizeth all, and having seized so blinds them as forgetting all rules of reason, they neither see nor hear any snare.

But then the old monk thinks that he has said enough about this subject and apologizes for his digression in another paragraph that should remove any lingering doubt there may be with regard to the genuineness of his monastic character. The personal element in his confession is so naive and so simply straightforward that instead of seeming to be the result of conceit, and so repelling the reader, it rather attracts his kindly feeling for its author. The paragraph would remind one in certain ways of that personal element that was to become more popular in literature after Montaigne had made such extensive use of it.

But of these enough; for it becomes not a religious man to insist too long upon these cogitations, or to give place to such a flame in his heart. Hitherto (without boasting I speak it) I have throughout the whole course of my life kept myself safe and free from it, and I pray and invoke God to vouchsafe me his Grace that I may keep holy and inviolate the faith which I have sworn, and live contented with my spiritual spouse, the Holy, Catholick Church. For no other reason have I alleaged these than that I might express the love with which all tinctures ought to be moved towards metals, if ever they be admitted by them into true friendship, and by love, which permeates the inmost parts, be converted into a better state

The application of the figure at the end of his long digression is characteristic of the period in which he wrote and to a considerable extent also of the German literary methods of the time.

In this volume on the use of antimony there are in most of the editions certain biographical notes which have sometimes been accepted as authentic, but oftener rejected. According to these, Basil Valentine was born in a town in Alsace, on the southern bank of the Rhine. As a consequence of this, there are several towns that have laid claim to being his birthplace. M. Jean Reynaud, the distinguished French philosophical writer of the first half of the nineteenth century, once said that Basil Valentine, like Ossian and Homer, had many towns claim him years after his death. He also suggested that, like those old poets, it was possible that the writings sometimes attributed to Basil Valentine were really the work not of one man, but of several individuals. There are, however, many objections to this theory, the most forceful of which is the internal evidence of the books themselves and their style and method of treatment. Other biographic details contained in "The Triumphal Chariot of Antimony" are undoubtedly more correct. According to them, Basil Valentine travelled in England and Holland on missions for his Order, and went through France and Spain on a pilgrimage to St. James of Compostella.

Besides this work, there is a number of other books of Basil Valentine's, printed during the first half of the sixteenth century, that are well-known and copies of which may be found in most of the important libraries. The United States Surgeon General's Library at Washington contains several of the works on medical subjects, and the New York Academy of Medicine Library has some valuable editions of his works. Some of his other well-known books, each of which is a good-sized octavo volume, bear the following descriptive titles (I give them in English, though, as they are usually to be found, they are in Latin, sixteenth-century translations of the original German): "The World in Miniature: or, The Mystery of the World and of Human Medical Science," published at Marburg, 1609;–"The Chemical Apocalypse: or, The Manifestation of Artificial Chemical Compounds," published at Erfurt in 1624;–"A Chemico-Philosophic Treatise Concerning Things Natural and Preternatural, Especially Relating to the Metals and the Minerals," published at Frankfurt in 1676;–"Haliography: or, The Science of Salts: A Treatise on the Preparation, Use and Chemical Properties of All the Mineral, Animal and Vegetable Salts," published at Bologna in 1644;–"The Twelve Keys of Philosophy," Leipsic, 1630.

The great interest manifested in Basil Valentine's work at the Renaissance period can be best realized from the number of manuscript copies and their wide distribution. His books were not all printed at one place, but, on the contrary, in different portions of Europe. The original edition of "The Triumphal Chariot of Antimony" was published at Leipsic in the early part of the sixteenth century. The first editions of the other books, however, appeared at places so distant from Leipsic as Amsterdam and Bologna, while various cities of Germany, as Erfurt and Frankfurt, claim the original editions of still other works. Many of the manuscript copies still exist in various libraries in Europe; and while there is no doubt that some unimportant additions to the supposed works of Basil Valentine have come from the attribution to him of scientific treatises of other German writers, the style and the method of the principal works mentioned are entirely too similar not to have been the fruit of a single mind and that possessed of a distinct investigating genius setting it far above any of its contemporaries in scientific speculation and observation.

The most interesting feature of all of Basil Valentine's writings that are extant is the distinctive tendency to make his observations of special practical utility. His studies in antimony were made mainly with the idea of showing how that substance might be used in medicine. He did not neglect to point out other possible uses, however, and knew the secret of the employment of antimony in order to give sharpness and definition to the impression produced by metal types. It would seem as though he was the first scientist who discussed this subject, and there is even some question whether printers and type founders did not derive their ideas in this matter from Basil Valentine, rather than he from them. Interested as he was in the transmutation of metals, he never failed to try to find and suggest some medicinal use for all of the substances that he investigated. His was no greedy search for gold and no accumulation of investigations with the idea of benefiting only himself. Mankind was always in his mind, and perhaps there is no better demonstration of his fulfilment of the character of the monk than this constant solicitude to benefit others by every bit of investigation that he carried out. For him with medieval nobleness of spirit the first part of every work must be the invocation of God, and the last, though no less important than the first, must be the utility and fruit for mankind that can be derived from it.

IV.

LINACRE: SCHOLAR, PHYSICIAN, PRIEST

Linacre, as Dr. Payne remarks, "was possessed from his youth till his death by the enthusiasm of learning. He was an idealist devoted to objects which the world thought of little use." Painstaking, accurate, critical, hypercritical perhaps, he remains to-day the chief literary representative of British Medicine. Neither in Britain nor in Greater Britain have we maintained the place in the world of letters created for us by Linacre's noble start. Quoted by Osler in AEquanimitas.

IV.

LINACRE: SCHOLAR, PHYSICIAN, PRIEST

Not long ago, in one of his piquant little essays, Mr. Augustine Birrell discussed the question as to what really happened at the time of the so-called Reformation in England. There is much more doubt with regard to this matter, even in the minds of non-Catholics, than is usually suspected. Mr. Birrell seems to have considered it one of the most important problems, and at the same time not by any means the least intricate one, in modern English history. The so-called High Church people emphatically insist that there is no break in the continuity of the Church of England, and that the modern Anglicanism is a direct descendant of the old British Church. They reject with scorn the idea that it was the Lutheran movement on the Continent which brought about the changes in the Anglican Church at that time. Protestantism did not come into England for a considerable period after the change in the constitution of the Anglican Church, and when it did come its tendencies were quite as subversal of the authority of the Anglican as of the Roman Church, Protestantism is the mother of Nonconformism in England. It can be seen, then, that the question as to what did really take place in the time of Henry VIII and of Edward VI is still open. It has seemed to me that no little light on this vexed historical question will be thrown by a careful study of the life of Dr. Linacre, who, besides being the best known physician of his time in England, was the greatest scholar of the English Renaissance period, yet had all his life been on very intimate terms with the ecclesiastical authorities, and eventually gave up his honors, his fortune, and his profession to become a simple priest of the old English Church.