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The Tangled Tree: A Radical New History of Life
The Tangled Tree: A Radical New History of Life
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The Tangled Tree: A Radical New History of Life

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The Tangled Tree: A Radical New History of Life
David Quammen

Our understanding of the ‘tree of life’, with powerful implications for human genetics, human health and our own human nature, has recently completely changed.This book is about a new method of telling the story of life on earth – through molecular phylogenetics. It involves a fairly simple method – the reading of the deep history of life by looking at the variation in protein molecules found in living organisms. For instance, we now know that roughly eight per cent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection.In The Tangled Tree, acclaimed science writer David Quammen chronicles these discoveries through the lives of the researchers who made them – such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about ‘mosaic’ creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.Quammen explains how molecular studies of evolution have brought startling recognitions about the tangled tree of life – including where we humans fit into it. Thanks to new technologies, we now have the ability to alter even our genetic composition – through sideways insertions, as nature has long been doing. The Tangled Tree is a brilliant exploration of our transformed understanding of evolution and of life’s history itself.

Copyright (#ulink_dbb67f5c-03d2-5831-ae2b-727bd8c24a72)

William Collins

An imprint of HarperCollinsPublishers

1 London Bridge Street

London SE1 9GF

WilliamCollinsBooks.com (http://WilliamCollinsBooks.com)

This eBook first published in Great Britain by William Collins in 2018

Copyright © David Quammen 2018

Jacket design by Jack Smyth

David Quammen asserts the moral right to be identified as the author of this work.

A catalogue record for this book is available from the British Library.

All rights reserved under International and Pan-American Copyright Conventions. By payment of the required fees, you have been granted the non-exclusive, non-transferable right to access and read the text of this e-book on-screen. No part of this text may be reproduced, transmitted, down-loaded, decompiled, reverse engineered, or stored in or introduced into any information storage and retrieval system, in any form or by any means, whether electronic or mechanical, now known or hereinafter invented, without the express written permission of HarperCollins.

Source ISBN: 9780008310684

eBook Edition © September 2018 ISBN: 9780008310691

Version: 2018-07-31

Dedication (#u7a661170-884b-549e-9fa6-984e55aed8fa)

To Dennis Hutchinson and David Roe, my attorneys of the soul

Contents

Cover (#u39fd20bd-0abf-5376-acf2-aee1dd5f8ccb)

Title Page (#u4d5e7a3c-0209-5dd2-9314-7aff0698ee1a)

Copyright (#u439d16cf-b147-5f6b-9921-17b294000e17)

Dedication

THREE SURPRISES: An Introduction

PART I: Darwin’s Little Sketch

Chapter 1

Chapter 2

Chapter 3

Chapter 4

Chapter 5

Chapter 6

Chapter 7

Chapter 8

PART II: A Separate Form of Life

Chapter 9

Chapter 10

Chapter 11

Chapter 12

Chapter 13

Chapter 14

Chapter 15

Chapter 16

Chapter 17

Chapter 18

Chapter 19

Chapter 20

Chapter 21

Chapter 22

Chapter 23

Chapter 24

Chapter 25

Chapter 26

Chapter 27

PART III: Mergers and Acquisitions

Chapter 28

Chapter 29

Chapter 30

Chapter 31

Chapter 32

Chapter 33

Chapter 34

Chapter 35

Chapter 36

PART IV: Big Tree

Chapter 37

Chapter 38

Chapter 39

Chapter 40

Chapter 41

Chapter 42

Chapter 43

Chapter 44

Chapter 45

Chapter 46

Chapter 47

Chapter 48

PART V: Infective Heredity

Chapter 49

Chapter 50

Chapter 51

Chapter 52

Chapter 53

Chapter 54

Chapter 55

Chapter 56

Chapter 57

Chapter 58

Chapter 59

PART VI: Topiary

Chapter 60

Chapter 61

Chapter 62

Chapter 63

Chapter 64

Chapter 65

Chapter 66

Chapter 67

Chapter 68

Chapter 69